John Paolini Biography and Net Worth

John joined the Kiniksa team in 2016 with over 25 years of experience spanning from basic biological/medical science through all phases of clinical development and regulatory strategy for small molecules and biologics. He was most recently clinical research head of the Cardiovascular and Metabolic Diseases Research Unit at Pfizer Inc., where he was responsible for bringing forward programs in diabetes, heart failure, lipids, and metabolic liver disease from preclinical through early clinical development and proof of concept. John previously served as Chief Medical Officer of Cerenis Therapeutics in France, a publicly traded company on the Euronext exchange. He was responsible for designing and executing clinical trials and regulatory strategy for a portfolio of products relating to HDL and reverse lipid transport and also played an instrumental role in the company’s capital-raising efforts, including its initial public offering. Before moving to France, John was Global Clinical Leader at Bayer HealthCare Pharma, where he was responsible for the Phase III program, NDA filing, and launch of Xarelto® in atrial fibrillation as well as Xarelto Life Cycle Management. He started in the pharmaceutical industry at Merck & Co., Inc., in cardiovascular clinical research and clinical pharmacology, leading programs in thrombosis and dyslipidemia that spanned the early- and late-stage portfolio, including Zocor® and Aggrastat®, the Vytorin®, Zetia®, and Tredaptive® clinical development programs and NDAs, as well as in-licensing activities in cardiovascular disease. John obtained an MD, PhD from Duke University, where his PhD work focused on the protein chemistry of immune mediators. He subsequently completed a residency in internal medicine and a fellowship in cardiovascular medicine at the Brigham and Women’s Hospital, including a postdoctoral fellowship at the Massachusetts Institute of Technology researching the role of inflammatory mediators in vascular disease and restenosis. He received Board certification in internal medicine and cardiology and is a Fellow of the American College of Cardiology. He was a member of the clinical faculty at the University of Pennsylvania as a clinical associate and served as an attending physician for 10 years, precepting cardiology fellows in the HUP outpatient cardiology clinic. John has authored more than 75 peer-reviewed journal articles and abstracts. He received a bachelor of arts, summa cum laude, and a bachelor of science, summa cum laude, from Tulane University.