IONS Insider Trading

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Insider Trading History
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About

Insider Ownership Percentage: 2.71%

Insider Buying (Last 12 Months): $181,100.00

Insider Selling (Last 12 Months): $5,063,297.91

Ionis Pharmaceuticals Insider Trading History Chart

Ionis Pharmaceuticals Share Price & Price History

^$27.90

▲ +1.19 (4.46%)

As of 04/11/2025 05:00 PM ET

Days: 30 | 90 | 365

Ionis Pharmaceuticals Insider Trading History

Transaction Date	Insider Name	Title	Buy/Sell	Number of Shares	Average Share Price	Total Transaction	Shares Held After Transaction
3/11/2025	Brett P. Monia	CEO	Sell	140	$32.32	$4,524.80	180,980
2/20/2025	Patrick R. O'Neil	EVP	Sell	1,207	$32.35	$39,046.45	56,245
2/4/2025	Brett P. Monia	CEO	Sell	38,843	$31.65	$1,229,380.95	180,683
2/4/2025	Patrick R. O'Neil	EVP	Sell	6,165	$31.62	$194,937.30	57,452
1/31/2025	Brett P. Monia	CEO	Sell	13,242	$32.45	$429,702.90	219,526
1/31/2025	Elizabeth L. Hougen	CFO	Sell	1,523	$32.44	$49,406.12	110,500
1/31/2025	Eric Swayze	EVP	Sell	1,367	$32.31	$44,167.77	48,017
1/16/2025	Brett P. Monia	CEO	Sell	33,445	$32.63	$1,091,310.35	207,396
1/16/2025	Elizabeth L. Hougen	CFO	Sell	8,870	$32.81	$291,024.70	107,885
1/16/2025	Eric Swayze	EVP	Sell	7,154	$32.84	$234,937.36	45,670
12/23/2024	Michael R. Hayden	Director	Buy	5,000	$36.22	$181,100.00	35,219
11/12/2024	Brett P. Monia	CEO	Sell	6,630	$38.05	$252,271.50	167,393
11/12/2024	Eric Swayze	EVP	Sell	1,194	$37.92	$45,276.48	33,713
10/16/2024	Eric Swayze	EVP	Sell	53	$38.31	$2,030.43	157
8/28/2024	Richard S. Geary	EVP	Sell	320	$49.16	$15,731.20	85,154
8/5/2024	Richard S. Geary	EVP	Sell	2,430	$48.00	$116,640.00	85,508
7/16/2024	Joseph Klein, III	Director	Sell	12,000	$50.00	$600,000.00	16,346
5/3/2024	Joseph Klein, III	Director	Sell	6,000	$42.71	$256,260.00	16,346
4/16/2024	Joseph Baroldi	EVP	Sell	4,006	$41.60	$166,649.60	19,631
2/16/2024	Brett P. Monia	CEO	Sell	387	$44.49	$17,217.63	173,751
2/2/2024	Brett P. Monia	CEO	Sell	23,501	$49.37	$1,160,244.37	174,138
2/2/2024	Elizabeth L. Hougen	CFO	Sell	2,125	$49.54	$105,272.50	92,905
2/2/2024	Eric Swayze	EVP	Sell	1,907	$49.56	$94,510.92	34,324
1/31/2024	Eric Swayze	EVP	Sell	10,773	$52.00	$560,196.00	32,516
1/25/2024	Brett P. Monia	CEO	Sell	2,285	$51.75	$118,248.75	151,851
1/25/2024	Patrick R. O'Neil	EVP	Sell	6,450	$51.75	$333,787.50	46,802
1/17/2024	Brett P. Monia	CEO	Sell	32,059	$50.42	$1,616,414.78	154,136
1/17/2024	Elizabeth L. Hougen	CFO	Sell	8,683	$50.42	$437,796.86	90,890
1/17/2024	Onaiza J. Cadoret-Manier	EVP	Sell	5,564	$50.42	$280,536.88	33,810
1/12/2024	Eugene Schneider	EVP	Sell	8,000	$53.50	$428,000.00	38,170
12/28/2023	B. Lynne Parshall, Esq.	Director	Sell	42,525	$50.19	$2,134,329.75	82,588
12/26/2023	B. Lynne Parshall, Esq.	Director	Sell	25,113	$51.46	$1,292,314.98	82,588
12/26/2023	Patrick R. O'Neil	EVP	Sell	20,825	$51.46	$1,071,654.50	40,355
12/21/2023	Brett P. Monia	CEO	Sell	17,500	$49.29	$862,575.00	118,111
12/20/2023	C. Frank Bennett	EVP	Sell	6,500	$49.64	$322,660.00	65,754
12/14/2023	Brett P. Monia	CEO	Sell	24,000	$49.58	$1,189,920.00	118,111
11/15/2023	Joseph Klein, III	Director	Sell	2,000	$50.00	$100,000.00	16,346
10/17/2023	Eric Swayze	EVP	Sell	52	$47.95	$2,493.40	73
10/12/2023	Brett P. Monia	CEO	Sell	3,770	$46.00	$173,420.00	118,111
9/28/2023	C. Frank Bennett	EVP	Sell	4,460	$46.50	$207,390.00	65,754
9/26/2023	B. Lynne Parshall, Esq.	Director	Sell	10,000	$45.13	$451,300.00	82,588
8/1/2023	Allene M. Diaz	Director	Sell	657	$41.05	$26,969.85	12,676
7/18/2023	Joseph Klein, III	Director	Sell	3,555	$42.00	$149,310.00	20,346
7/7/2023	Brett P. Monia	CEO	Sell	18,650	$42.25	$787,962.50	121,724
5/24/2023	Patrick R. O'Neil	EVP	Sell	1,527	$41.70	$63,675.90	40,355
5/22/2023	Brett P. Monia	CEO	Sell	4,931	$40.14	$197,930.34	140,374
4/18/2023	Brian Birchler	EVP	Sell	672	$36.50	$24,528.00	36,528
2/6/2023	Brett P. Monia	CEO	Sell	24,651	$40.69	$1,003,049.19	145,305
2/6/2023	Elizabeth L. Hougen	CFO	Sell	2,079	$40.59	$84,386.61	75,496
2/6/2023	Eric Swayze	EVP	Sell	1,815	$40.79	$74,033.85	31,941
1/30/2023	Patrick R. O'Neil	EVP	Sell	4,500	$39.42	$177,390.00	44,179
1/18/2023	Brett P. Monia	CEO	Sell	25,066	$39.49	$989,856.34	120,863
1/18/2023	Elizabeth L. Hougen	CFO	Sell	8,280	$39.70	$328,716.00	73,435
1/18/2023	Eric Swayze	EVP	Sell	5,631	$39.74	$223,775.94	30,041
1/17/2023	Joseph Klein, III	Director	Sell	2,000	$40.00	$80,000.00	16,791
9/8/2022	Eric Swayze	EVP	Sell	460	$44.55	$20,493.00	19,892
7/15/2022	Joseph Klein, III	Director	Sell	1,333	$38.24	$50,973.92	18,791
4/21/2022	Eric Swayze	EVP	Sell	378	$44.15	$16,688.70	20,353
4/12/2022	Patrick R. O'Neil	EVP	Sell	6,792	$40.06	$272,087.52	34,536

See Full Table

SEC Filings (Institutional Ownership Changes) for Ionis Pharmaceuticals (NASDAQ:IONS)

93.86% of Ionis Pharmaceuticals stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

Ionis Pharmaceuticals Institutional Trading History

Reporting Date	Hedge Fund	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
4/8/2025	Rhumbline Advisers	188,216	$5.68M	0.0%	-1.9%	0.118%
4/7/2025	GAMMA Investing LLC	28,993	$0.96M	0.0%	+3,786.5%	0.018%
3/18/2025	California State Teachers Retirement System	133,902	$4.68M	0.0%	+6.1%	0.084%
2/19/2025	GF Fund Management CO. LTD.	3,315	$0.12M	0.0%	N/A	0.002%
2/19/2025	Public Employees Retirement System of Ohio	53,748	$1.88M	0.0%	-5.4%	0.034%
2/17/2025	UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	619,641	$21.66M	0.0%	-40.8%	0.392%
2/17/2025	Voloridge Investment Management LLC	316,943	$11.08M	0.0%	-16.7%	0.201%
2/17/2025	Woodline Partners LP	107,610	$3.76M	0.0%	N/A	0.068%
2/17/2025	Vestal Point Capital LP	595,000	$20.80M	1.2%	N/A	0.377%
2/17/2025	Two Sigma Advisers LP	1,349,211	$47.17M	0.1%	+1.3%	0.854%
2/17/2025	Two Sigma Investments LP	921,439	$32.21M	0.1%	+0.3%	0.584%
2/17/2025	Tidal Investments LLC	17,407	$0.61M	0.0%	-7.9%	0.011%
2/17/2025	Teza Capital Management LLC	8,525	$0.30M	0.0%	-19.6%	0.005%
2/17/2025	Tanaka Capital Management Inc.	6,892	$0.24M	0.6%	-52.5%	0.004%
2/17/2025	Tema Etfs LLC	56,844	$1.99M	0.8%	N/A	0.036%
2/17/2025	Silvercrest Asset Management Group LLC	6,617	$0.23M	0.0%	N/A	0.004%
2/17/2025	Rafferty Asset Management LLC	237,337	$8.30M	0.0%	+19.4%	0.150%
2/17/2025	Raiffeisen Bank International AG	1,754	$62K	0.0%	N/A	0.001%
2/17/2025	ProShare Advisors LLC	7,480	$0.26M	0.0%	-13.4%	0.005%
2/17/2025	Nuveen Asset Management LLC	290,954	$10.17M	0.0%	-96.9%	0.184%
2/17/2025	OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC	60,580	$2.12M	0.2%	+63.9%	0.038%
2/17/2025	Orbimed Advisors LLC	2,817,347	$98.49M	2.2%	+21.2%	1.784%
2/17/2025	Millennium Management LLC	774,215	$27.07M	0.0%	+79.7%	0.490%
2/17/2025	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	9,450	$0.33M	0.0%	+20.8%	0.006%
2/17/2025	J. Goldman & Co LP	607,499	$21.24M	0.6%	+17.1%	0.385%
2/17/2025	Jacobs Levy Equity Management Inc.	281,813	$9.85M	0.0%	-56.7%	0.178%
2/17/2025	Janus Henderson Group PLC	63,877	$2.23M	0.0%	+8.3%	0.040%
2/17/2025	Hudson Bay Capital Management LP	821,200	$28.71M	0.1%	+7.1%	0.520%
2/17/2025	Focus Partners Wealth	7,555	$0.28M	0.0%	+32.6%	0.005%
2/17/2025	Ensign Peak Advisors Inc	53,320	$1.86M	0.0%	-23.7%	0.034%
2/17/2025	D. E. Shaw & Co. Inc.	23,123	$0.81M	0.0%	-84.1%	0.015%
2/17/2025	Driehaus Capital Management LLC	180,002	$6.29M	0.1%	-21.7%	0.114%
2/17/2025	Deep Track Capital LP	1,933,928	$67.61M	2.5%	-12.1%	1.225%
2/17/2025	Caption Management LLC	5,417	$0.19M	0.0%	-93.5%	0.003%
2/17/2025	Brevan Howard Capital Management LP	21,366	$0.75M	0.0%	-25.0%	0.014%
2/17/2025	Bridgefront Capital LLC	21,802	$0.76M	0.3%	+94.7%	0.014%
2/17/2025	Bellevue Group AG	7,868,700	$275.09M	5.3%	-0.1%	4.983%
2/17/2025	Alyeska Investment Group L.P.	150,000	$5.24M	0.0%	-11.2%	0.095%
2/17/2025	Allostery Investments LP	65,000	$2.27M	2.4%	N/A	0.041%
2/14/2025	BlueCrest Capital Management Ltd	26,200	$0.92M	0.0%	N/A	0.017%
2/14/2025	Comerica Bank	7,393	$0.26M	0.0%	-30.4%	0.005%
2/14/2025	PDT Partners LLC	28,994	$1.01M	0.1%	+116.4%	0.018%
2/14/2025	Schonfeld Strategic Advisors LLC	371,381	$12.98M	0.1%	+2.3%	0.235%
2/14/2025	Northern Trust Corp	840,271	$29.38M	0.0%	+13.1%	0.532%
2/14/2025	The Manufacturers Life Insurance Company	286,279	$10.01M	0.0%	-7.3%	0.181%
2/14/2025	Quarry LP	6,000	$0.21M	0.0%	N/A	0.004%
2/14/2025	Aquatic Capital Management LLC	230,016	$8.04M	0.2%	N/A	0.146%
2/14/2025	Susquehanna Fundamental Investments LLC	213,015	$7.45M	0.1%	N/A	0.135%
2/14/2025	Ghisallo Capital Management LLC	100,000	$3.50M	0.2%	-75.0%	0.063%
2/14/2025	Virtus ETF Advisers LLC	9,448	$0.33M	0.1%	+18.0%	0.006%
2/14/2025	Adage Capital Partners GP L.L.C.	275,000	$9.61M	0.0%	-45.0%	0.174%
2/14/2025	Syon Capital LLC	10,119	$0.35M	0.0%	N/A	0.006%
2/14/2025	T. Rowe Price Investment Management Inc.	14,169,199	$495.36M	0.3%	+0.0%	8.974%
2/14/2025	Price T Rowe Associates Inc. MD	3,826,939	$133.79M	0.0%	-9.1%	2.424%
2/14/2025	Eversept Partners LP	214,952	$7.52M	0.7%	-54.4%	0.136%
2/14/2025	Hsbc Holdings PLC	83,055	$2.93M	0.0%	N/A	0.053%
2/14/2025	Stifel Financial Corp	211,493	$7.39M	0.0%	+15.9%	0.134%
2/14/2025	Tower Research Capital LLC TRC	14,157	$0.50M	0.0%	+229.2%	0.009%
2/14/2025	Natixis	16,626	$0.58M	0.0%	N/A	0.011%
2/14/2025	Capital World Investors	11,465,413	$400.83M	0.1%	+46.5%	7.261%
2/14/2025	Commerce Bank	13,584	$0.48M	0.0%	-82.5%	0.009%
2/13/2025	CANADA LIFE ASSURANCE Co	39,214	$1.37M	0.0%	-1.6%	0.025%
2/13/2025	Canada Pension Plan Investment Board	19,900	$0.70M	0.0%	+77.7%	0.013%
2/13/2025	Marshall Wace LLP	812,306	$28.40M	0.0%	-57.7%	0.514%
2/13/2025	Jump Financial LLC	39,737	$1.39M	0.0%	-98.0%	0.025%
2/13/2025	Guggenheim Capital LLC	35,373	$1.24M	0.0%	-4.8%	0.022%
2/13/2025	XTX Topco Ltd	25,362	$0.89M	0.1%	+50.9%	0.016%
2/13/2025	Mariner LLC	27,661	$0.97M	0.0%	+19.6%	0.018%
2/13/2025	Granite Investment Partners LLC	73,866	$2.58M	0.1%	-13.9%	0.047%
2/13/2025	Kennedy Capital Management LLC	223,278	$7.81M	0.2%	+37.8%	0.141%
2/13/2025	Treasurer of the State of North Carolina	68,803	$2.41M	0.0%	+0.6%	0.044%
2/13/2025	Raymond James Financial Inc.	105,619	$3.69M	0.0%	N/A	0.067%
2/13/2025	Renaissance Technologies LLC	205,514	$7.19M	0.0%	+7.9%	0.130%
2/13/2025	Legal & General Group Plc	168,080	$5.88M	0.0%	-1.9%	0.106%
2/13/2025	Envestnet Asset Management Inc.	52,688	$1.84M	0.0%	-10.4%	0.033%
2/13/2025	Rhenman & Partners Asset Management AB	212,500	$7.43M	0.8%	+9.0%	0.135%
2/13/2025	Orion Investment Co	216,000	$7.55M	3.0%	-1.2%	0.137%
2/12/2025	Landscape Capital Management L.L.C.	10,270	$0.36M	0.0%	-59.6%	0.007%
2/12/2025	Annis Gardner Whiting Capital Advisors LLC	10,736	$0.38M	0.1%	+8.1%	0.007%
2/12/2025	Huntington National Bank	951	$33K	0.0%	+193.5%	0.001%
2/12/2025	Groupama Asset Managment	1,017,191	$35.56M	0.3%	+11.0%	0.644%
2/12/2025	Trexquant Investment LP	84,913	$2.97M	0.0%	-35.1%	0.054%
2/12/2025	Tweedy Browne Co LLC	3,248,863	$113.58M	7.7%	-6.0%	2.058%
2/12/2025	Geode Capital Management LLC	2,687,248	$93.98M	0.0%	+0.7%	1.702%
2/12/2025	Nicollet Investment Management Inc.	19,786	$0.69M	0.2%	-3.0%	0.013%
2/12/2025	Franklin Resources Inc.	13,301	$0.47M	0.0%	+31.0%	0.008%
2/12/2025	Clearbridge Investments LLC	1,618,220	$56.57M	0.0%	-4.9%	1.025%
2/12/2025	CIBC Private Wealth Group LLC	1,125	$38K	0.0%	-53.6%	0.001%
2/12/2025	California Public Employees Retirement System	192,130	$6.72M	0.0%	-9.3%	0.122%
2/12/2025	Schroder Investment Management Group	100,659	$3.52M	0.0%	-98.0%	0.064%
2/12/2025	Pictet Asset Management Holding SA	620,798	$21.70M	0.0%	-52.4%	0.393%
2/12/2025	Norges Bank	1,714,762	$59.95M	0.0%	N/A	1.086%
2/12/2025	Blair William & Co. IL	39,882	$1.39M	0.0%	-14.5%	0.025%
2/12/2025	NEOS Investment Management LLC	56,844	$1.99M	0.0%	-4.1%	0.036%
2/12/2025	Artisan Partners Limited Partnership	252,635	$8.83M	0.0%	-88.7%	0.160%
2/11/2025	EntryPoint Capital LLC	6,382	$0.22M	0.1%	N/A	0.004%
2/11/2025	Vanguard Group Inc.	16,472,539	$575.88M	0.0%	+9.4%	10.432%
2/11/2025	Stevens Capital Management LP	5,860	$0.21M	0.1%	N/A	0.004%
2/11/2025	LPL Financial LLC	40,376	$1.41M	0.0%	-5.3%	0.026%
2/11/2025	Harbor Advisors LLC	10,500	$0.37M	0.1%	+90.9%	0.007%

Data available starting January 2016

See Full Table

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.

Today's Range

Now: $27.90

$26.30

$27.97

50 Day Range

MA: $31.22

$25.51

$34.39

52 Week Range

Now: $27.90

$23.95

$52.34

Volume

2,010,951 shs

Average Volume

1,506,022 shs

Market Capitalization

$4.44 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.29

Who are the company insiders with the largest holdings of Ionis Pharmaceuticals?: Ionis Pharmaceuticals' top insider investors include:
Brett P Monia (CEO)
Elizabeth L Hougen (CFO)
Richard S Geary (EVP)
B Lynne Parshall (Director)
C Frank Bennett (EVP)
Patrick R O'neil (EVP)
Eric Swayze (EVP)
Eugene Schneider (EVP)
Brian Birchler (EVP)
Michael R Hayden (Director)
Onaiza Cadoret-Manier (EVP)
Joseph Klein III (Director)
Joseph Baroldi (EVP)
Allene M Diaz (Director)
Learn More about top insider investors at Ionis Pharmaceuticals.
Who are the major institutional investors of Ionis Pharmaceuticals?: Ionis Pharmaceuticals' top institutional shareholders include:
Rhumbline Advisers — 0.12%
GAMMA Investing LLC — 0.02%
Learn More about top institutional investors of Ionis Pharmaceuticals stock.
Which institutional investors are selling Ionis Pharmaceuticals stock?: In the last quarter, IONS stock was sold by these institutional investors:
Rhumbline Advisers
In the previous year, company insiders that have sold Ionis Pharmaceuticals company stock include:
Brett P Monia (CEO)
Elizabeth L Hougen (CFO)
Richard S Geary (EVP)
B Lynne Parshall (Director)
C Frank Bennett (EVP)
Patrick R O'neil (EVP)
Eric Swayze (EVP)
Learn More investors selling Ionis Pharmaceuticals stock.
Which institutional investors are buying Ionis Pharmaceuticals stock?: During the last quarter, IONS stock was purchased by institutional investors including:
GAMMA Investing LLC