GBT Insider Trading

Reporting Date	Hedge Fund	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
12/8/2022	Bank of New York Mellon Corp	272,788	$18.58M	0.0%	+7.3%	0.404%
11/22/2022	Mint Tower Capital Management B.V.	790	$54K	0.0%	N/A	0.001%
11/17/2022	Westchester Capital Management LLC	405,863	$27.64M	0.6%	N/A	0.601%
11/17/2022	Telemetry Investments L.L.C.	3,200	$0.22M	0.3%	N/A	0.005%
11/15/2022	Dana Investment Advisors Inc.	5,063	$0.35M	0.0%	N/A	0.008%
11/15/2022	Algert Global LLC	21,393	$1.46M	0.1%	-46.3%	0.032%
11/15/2022	TIG Advisors LLC	696,420	$47.43M	1.7%	N/A	1.032%
11/15/2022	Two Sigma Advisers LP	1,152,900	$78.51M	0.2%	+245.1%	1.709%
11/15/2022	Two Sigma Investments LP	314,839	$21.44M	0.1%	+84.3%	0.467%
11/15/2022	Twin Securities Inc.	376,669	$25.65M	11.9%	N/A	0.558%
11/15/2022	Perceptive Advisors LLC	2,322,247	$158.15M	4.6%	-23.0%	3.442%
11/15/2022	Prelude Capital Management LLC	125,029	$8.51M	0.3%	N/A	0.185%
11/15/2022	Parallax Volatility Advisers L.P.	5,221	$0.36M	0.0%	N/A	0.008%
11/15/2022	PenderFund Capital Management Ltd.	3,380	$0.32M	0.1%	N/A	0.005%
11/15/2022	Kellner Capital LLC	33,235	$2.26M	1.3%	N/A	0.049%
11/15/2022	Kynam Capital Management LP	131,220	$8.94M	1.9%	-94.0%	0.194%
11/15/2022	Marshall Wace LLP	103,490	$7.05M	0.0%	+1.6%	0.153%
11/15/2022	Edgestream Partners L.P.	28,226	$1.92M	0.1%	N/A	0.042%
11/15/2022	Ensign Peak Advisors Inc	168,180	$11.45M	0.0%	+81.3%	0.249%
11/15/2022	Farallon Capital Management LLC	450,000	$30.65M	0.2%	N/A	0.667%
11/15/2022	Fifth Lane Capital LP	117,300	$7.99M	4.2%	N/A	0.174%
11/15/2022	First Trust Capital Management L.P.	349,165	$23.78M	1.1%	N/A	0.517%
11/15/2022	Bison Wealth LLC	8,128	$0.55M	0.2%	N/A	0.012%
11/15/2022	BlackRock Inc.	4,749,863	$323.47M	0.0%	-0.5%	7.039%
11/15/2022	Cantor Fitzgerald L. P.	6,000	$0.41M	0.0%	N/A	0.009%
11/15/2022	Carlson Capital L P	400,000	$27.24M	2.1%	N/A	0.593%
11/14/2022	GABELLI & Co INVESTMENT ADVISERS INC.	231,506	$15.77M	2.0%	N/A	0.343%
11/14/2022	Gamco Investors INC. ET AL	46,544	$3.17M	0.0%	N/A	0.069%
11/14/2022	Gabelli Funds LLC	432,378	$29.45M	0.2%	+2,152.0%	0.641%
11/14/2022	Royal Bank of Canada	201,624	$13.73M	0.0%	-51.8%	0.299%
11/14/2022	Pentwater Capital Management LP	3,200,000	$217.92M	2.4%	N/A	4.742%
11/14/2022	Tudor Investment Corp Et Al	250,091	$17.03M	0.4%	+437.1%	0.371%
11/14/2022	Virtus ETF Advisers LLC	10,558	$0.72M	0.3%	+1.5%	0.016%
11/14/2022	Point72 Hong Kong Ltd	2,595	$0.18M	0.0%	N/A	0.004%
11/14/2022	Cubist Systematic Strategies LLC	32,834	$2.24M	0.0%	-47.5%	0.049%
11/14/2022	Guggenheim Capital LLC	28,129	$1.92M	0.0%	N/A	0.042%
11/14/2022	Glazer Capital LLC	1,412,219	$96.17M	1.8%	N/A	2.093%
11/14/2022	Renaissance Technologies LLC	283,700	$19.32M	0.0%	N/A	0.420%
11/14/2022	Verition Fund Management LLC	80,094	$5.45M	0.1%	N/A	0.119%
11/14/2022	Lazard Asset Management LLC	1,815	$0.12M	0.0%	N/A	0.003%
11/14/2022	Boothbay Fund Management LLC	43,670	$2.97M	0.1%	N/A	0.065%
11/14/2022	Ergoteles LLC	96,027	$6.54M	0.2%	+1,032.0%	0.142%
11/14/2022	Nuveen Asset Management LLC	589,525	$40.15M	0.0%	-9.3%	0.874%
11/14/2022	Canada Pension Plan Investment Board	88,100	$6M	0.0%	+5.9%	0.131%
11/14/2022	Water Island Capital LLC	649,242	$44.21M	2.5%	N/A	0.962%
11/14/2022	Healthcare of Ontario Pension Plan Trust Fund	316,521	$21.56M	0.1%	N/A	0.469%
11/14/2022	FORA Capital LLC	17,528	$1.19M	0.2%	N/A	0.026%
11/14/2022	UBS Oconnor LLC	2,238,787	$152.46M	2.9%	N/A	3.318%
11/14/2022	MetLife Investment Management LLC	33,813	$2.30M	0.0%	+1.9%	0.050%
11/14/2022	Shell Asset Management Co.	2,214	$0.15M	0.0%	-20.0%	0.003%
11/14/2022	Hsbc Holdings PLC	189,723	$12.93M	0.0%	N/A	0.281%
11/14/2022	E Fund Management Co. Ltd.	7,030	$0.48M	0.0%	-63.7%	0.010%
11/14/2022	Pictet Asset Management SA	100,199	$6.82M	0.0%	+8.7%	0.148%
11/14/2022	Skandinaviska Enskilda Banken AB publ	15,000	$1.02M	0.0%	N/A	0.022%
11/14/2022	Longfellow Investment Management Co. LLC	533	$36K	0.0%	N/A	0.001%
11/14/2022	DLD Asset Management LP	50,000	$3.41M	0.3%	N/A	0.074%
11/14/2022	CenterBook Partners LP	6,046	$0.41M	0.1%	N/A	0.009%
11/14/2022	Hennion & Walsh Asset Management Inc.	124,483	$8.48M	0.6%	+0.9%	0.184%
11/10/2022	Alpine Associates Management Inc.	743,397	$50.63M	2.1%	N/A	1.102%
11/10/2022	Credit Suisse AG	131,712	$8.97M	0.0%	+149.9%	0.195%
11/10/2022	Gabelli Funds LLC	432,378	$29.45M	0.2%	+2,152.0%	0.641%
11/10/2022	Gamco Investors INC. ET AL	46,544	$3.17M	0.0%	N/A	0.069%
11/10/2022	GABELLI & Co INVESTMENT ADVISERS INC.	231,506	$15.77M	2.0%	N/A	0.343%
11/10/2022	WINTON GROUP Ltd	20,528	$1.40M	0.1%	-12.3%	0.030%
11/10/2022	Wolverine Asset Management LLC	27,431	$1.87M	0.0%	N/A	0.041%
11/10/2022	Tower Research Capital LLC TRC	13,771	$0.94M	0.0%	-8.1%	0.020%
11/10/2022	Bank of Montreal Can	186,080	$12.69M	0.0%	N/A	0.276%
11/10/2022	UBS Group AG	276,847	$18.85M	0.0%	+155.2%	0.410%
11/9/2022	Amalgamated Bank	10,450	$0.71M	0.0%	+5.9%	0.015%
11/9/2022	BTG Pactual Global Asset Management Ltd	36,771	$2.50M	0.7%	N/A	0.054%
11/9/2022	Picton Mahoney Asset Management	221,191	$15.06M	0.5%	N/A	0.328%
11/9/2022	Chicago Capital Management LLC	246,246	$16.77M	9.1%	N/A	0.365%
11/9/2022	Zurcher Kantonalbank Zurich Cantonalbank	10,291	$0.70M	0.0%	-76.8%	0.015%
11/9/2022	California Public Employees Retirement System	158,222	$10.78M	0.0%	N/A	0.234%
11/9/2022	Fernwood Investment Management LLC	174,724	$11.90M	5.0%	-13.8%	0.259%
11/8/2022	Allianz Asset Management GmbH	401,197	$27.32M	0.1%	N/A	0.595%
11/8/2022	State Board of Administration of Florida Retirement System	20,154	$1.37M	0.0%	-25.2%	0.030%
11/8/2022	New York State Common Retirement Fund	46,558	$3.17M	0.0%	+3.6%	0.069%
11/8/2022	OLD National Bancorp IN	4,484	$0.31M	0.0%	-61.0%	0.007%
11/8/2022	BCK Capital Management LP	18,098	$1.23M	0.9%	N/A	0.027%
11/7/2022	Quantbot Technologies LP	10,300	$0.70M	0.1%	+51.2%	0.015%
11/7/2022	Jump Financial LLC	62,589	$4.26M	0.2%	+79.0%	0.093%
11/7/2022	ProShare Advisors LLC	12,797	$0.87M	0.0%	+6.0%	0.019%
11/4/2022	Vontobel Holding Ltd.	10,000	$0.68M	0.0%	N/A	0.015%
11/4/2022	Prudential Financial Inc.	4,754	$0.32M	0.0%	N/A	0.007%
11/4/2022	First Republic Investment Management Inc.	15,431	$1.05M	0.0%	-15.6%	0.023%
11/3/2022	Teacher Retirement System of Texas	20,234	$1.38M	0.0%	+117.5%	0.030%
11/3/2022	The Manufacturers Life Insurance Company	24,276	$1.65M	0.0%	-42.7%	0.036%
11/3/2022	Barclays PLC	130,434	$8.88M	0.0%	-77.9%	0.193%
11/2/2022	Los Angeles Capital Management LLC	8,846	$0.60M	0.0%	N/A	0.013%
10/31/2022	Calton & Associates Inc.	6,016	$0.41M	0.2%	N/A	0.009%
10/31/2022	SG Americas Securities LLC	8,674	$0.59M	0.0%	-82.2%	0.013%
10/31/2022	Dupont Capital Management Corp	9,567	$0.65M	0.0%	N/A	0.014%
10/28/2022	State of New Jersey Common Pension Fund D	37,665	$2.57M	0.0%	-53.5%	0.056%
10/27/2022	Assenagon Asset Management S.A.	590,153	$40.19M	0.2%	+249.7%	0.875%
10/27/2022	Strs Ohio	11,900	$0.81M	0.0%	N/A	0.018%
10/26/2022	Allspring Global Investments Holdings LLC	940	$64K	0.0%	-78.3%	0.001%
10/25/2022	Versor Investments LP	641,904	$43.71M	2.6%	N/A	0.951%
10/24/2022	Xponance Inc.	3,624	$0.25M	0.0%	N/A	0.005%
10/24/2022	Mizuho Markets Americas LLC	255,749	$17.42M	0.8%	+35.8%	0.379%

Data available starting January 2016

Global Blood Therapeutics, Inc., a biopharmaceutical company, engages in the discovery, development, and delivery of treatments for underserved patient communities with sickle cell disease (SCD). The company offers Oxbryta tablets, an oral, once-daily therapy for SCD. It also evaluates the safety and pharmacokinetics of single and multiple doses of Oxbryta in a Phase II a clinical trial of adolescent and pediatric patients with SCD. In addition, the company is developing its lead product candidate inclacumab, novel human monoclonal antibody, which is in Phase III a clinical trial to reduce the incidence of painful vaso-occlusive crises, and resulting hospital admissions; and GBT601, a hemoglobin polymerization inhibitor that is in Phase I development. It has a license and collaboration agreement with Syros Pharmaceuticals, Inc. to discover, develop, and commercialize therapies for SCD and beta thalassemia; and Sanofi S.A. to two early-stage research programs in SCD. Global Blood Therapeutics, Inc. was incorporated in 2011 and is headquartered in South San Francisco, California.

Today's Range

Now: $68.49

$68.49

50 Day Range

MA: $68.47

$68.07

$68.49

52 Week Range

Now: $68.49

$21.65

$73.02

Volume

74 shs

Average Volume

2,065,836 shs

Market Capitalization

$4.62 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.45

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