DNLI Insider Trading

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Insider Trading History
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About

Insider Ownership Percentage: 7.90%

Insider Buying (Last 12 Months): $0.00

Insider Selling (Last 12 Months): $4,158,155.65

Denali Therapeutics Insider Trading History Chart

Denali Therapeutics Share Price & Price History

^$16.50

▲ +0.25 (1.54%)

As of 04/29/2025 05:00 PM ET

Days: 30 | 90 | 365

Denali Therapeutics Insider Trading History

Transaction Date	Insider Name	Title	Buy/Sell	Number of Shares	Average Share Price	Total Transaction	Shares Held After Transaction
1/7/2025	Steve E Krognes	Director	Sell	3,339	$20.81	$69,484.59	25,757
1/6/2025	Carole Ho	Insider	Sell	12,255	$20.22	$247,796.10	178,580
1/6/2025	Ryan J Watts	CEO	Sell	29,266	$20.22	$591,758.52	260,721
1/2/2025	Vicki L. Sato	Director	Sell	3,080	$20.91	$64,402.80	107,976
11/7/2024	Alexander O Schuth	Insider	Sell	15,558	$29.91	$465,339.78	178,066
11/7/2024	Vicki L. Sato	Director	Sell	1,020	$30.00	$30,600.00	111,056
10/18/2024	Ryan J Watts	CEO	Sell	40,000	$27.69	$1,107,600.00	235,807
9/30/2024	Steve E Krognes	Director	Sell	30,000	$29.03	$870,900.00	29,096
7/1/2024	Steve E Krognes	Director	Sell	30,000	$22.12	$663,600.00	34,404
6/13/2024	Steve E Krognes	Director	Sell	688	$21.79	$14,991.52	52,620
6/6/2024	Jennifer E. Cook	Director	Sell	1,458	$21.73	$31,682.34	20,038
4/15/2024	Vicki L. Sato	Director	Sell	1,666	$18.29	$30,471.14	118,043
4/1/2024	Steve E Krognes	Director	Sell	92,500	$20.50	$1,896,250.00	47,341
2/15/2024	Vicki L. Sato	Director	Sell	1,666	$18.37	$30,604.42	121,375
2/13/2024	Carole Ho	Insider	Sell	2,784	$17.29	$48,135.36	145,010
2/13/2024	Ryan J Watts	CEO	Sell	9,589	$17.29	$165,793.81	238,067
2/13/2024	Steve E Krognes	Director	Sell	2,750	$17.29	$47,547.50	139,841
1/16/2024	Vicki L. Sato	Director	Sell	1,666	$18.42	$30,687.72	123,041
1/10/2024	Carole Ho	Insider	Sell	4,668	$19.02	$88,785.36	147,794
1/9/2024	Ryan J Watts	CEO	Sell	7,818	$19.78	$154,640.04	2,268,363
1/5/2024	Carole Ho	Insider	Sell	9,972	$19.43	$193,755.96	198,777
1/5/2024	Ryan J Watts	CEO	Sell	17,483	$19.43	$339,694.69	2,276,181
1/5/2024	Steve E Krognes	Director	Sell	3,208	$19.43	$62,331.44	142,591
12/15/2023	Vicki L. Sato	Director	Sell	1,666	$23.39	$38,967.74	124,707
11/15/2023	Vicki L. Sato	Director	Sell	1,666	$19.13	$31,870.58	126,373
10/16/2023	Vicki L. Sato	Director	Sell	1,666	$20.66	$34,419.56	128,039
9/15/2023	Vicki L. Sato	Director	Sell	1,666	$23.62	$39,350.92	129,705
8/23/2023	Carole Ho	Insider	Sell	2,522	$23.22	$58,560.84	182,809
8/21/2023	Carole Ho	Insider	Sell	2,478	$22.60	$56,002.80	185,331
8/21/2023	Carole Ho	Insider	Sell	2,478	$22.60	$56,002.80	185,331
8/21/2023	Ryan J Watts	CEO	Sell	2,309	$22.59	$52,160.31	2,242,604
8/21/2023	Ryan J Watts	CEO	Sell	2,309	$22.59	$52,160.31	2,242,604
8/21/2023	Steve E Krognes	Director	Sell	1,419	$22.60	$32,069.40	145,799
8/21/2023	Steve E Krognes	Director	Sell	1,419	$22.60	$32,069.40	145,799
8/15/2023	Vicki L. Sato	Director	Sell	1,666	$24.30	$40,483.80	131,371
8/14/2023	Carole Ho	Insider	Sell	2,768	$23.79	$65,850.72	182,809
8/10/2023	Carole Ho	Insider	Sell	2,857	$24.15	$68,996.55	185,577
8/10/2023	Ryan J Watts	CEO	Sell	2,526	$25.03	$63,225.78	2,239,913
7/17/2023	Alexander O Schuth	Insider	Sell	10,000	$29.60	$296,000.00	528,691
7/17/2023	Vicki L. Sato	Director	Sell	1,666	$29.60	$49,313.60	133,037
6/28/2023	Vicki L. Sato	Director	Sell	1,666	$29.84	$49,713.44	134,703
5/15/2023	Alexander O Schuth	Insider	Sell	10,000	$28.60	$286,000.00	528,691
4/20/2023	Ryan J Watts	CEO	Sell	200	$25.00	$5,000.00	2,239,913
4/12/2023	Alexander O Schuth	Insider	Sell	5,102	$25.04	$127,754.08	528,691
2/13/2023	Carole Ho	Insider	Sell	2,548	$30.10	$76,694.80	184,285
2/13/2023	Ryan J Watts	CEO	Sell	33,815	$30.08	$1,017,155.20	2,239,913
2/13/2023	Steve E Krognes	Director	Sell	2,119	$30.10	$63,781.90	143,002
2/10/2023	Carole Ho	Insider	Sell	818	$29.80	$24,376.40	179,365
2/10/2023	Ryan J Watts	CEO	Sell	25,000	$29.10	$727,500.00	2,229,031
2/8/2023	Carole Ho	Insider	Sell	1,521	$30.88	$46,968.48	180,183
2/8/2023	Steve E Krognes	Director	Sell	1,377	$30.88	$42,521.76	145,121
1/17/2023	Alexander O Schuth	Insider	Sell	10,000	$29.53	$295,300.00	497,173
1/9/2023	Carole Ho	Insider	Sell	1,459	$28.48	$41,552.32	177,454
1/6/2023	Carole Ho	Insider	Sell	1,451	$28.67	$41,600.17	178,913
1/5/2023	Steve E Krognes	Director	Sell	2,970	$28.44	$84,466.80	146,498
1/4/2023	Carole Ho	Insider	Sell	2,913	$28.69	$83,573.97	175,500
1/4/2023	Ryan J Watts	CEO	Sell	5,029	$28.73	$144,483.17	2,213,464
11/23/2022	Marc Tessier-Lavigne	Director	Sell	20,000	$30.48	$609,600.00	1,870,356
11/1/2022	Marc Tessier-Lavigne	Director	Sell	8,748	$30.20	$264,189.60	1,901,608
9/28/2022	Marc Tessier-Lavigne	Director	Sell	20,000	$30.82	$616,400.00	1,910,356
8/23/2022	Carole Ho	Insider	Sell	2,424	$31.98	$77,519.52	170,663
8/23/2022	Marc Tessier-Lavigne	Director	Sell	20,000	$31.61	$632,200.00	1,930,356
8/19/2022	Alexander O Schuth	Insider	Sell	2,576	$33.22	$85,574.72	467,471
8/19/2022	Ryan J Watts	CEO	Sell	2,404	$33.22	$79,860.88	2,202,993
8/19/2022	Steve E Krognes	Director	Sell	2,253	$33.22	$74,844.66	149,468
7/25/2022	Marc Tessier-Lavigne	Director	Sell	20,000	$35.61	$712,200.00	1,950,356

See Full Table

SEC Filings (Institutional Ownership Changes) for Denali Therapeutics (NASDAQ:DNLI)

92.92% of Denali Therapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

Denali Therapeutics Institutional Trading History

Reporting Date	Hedge Fund	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
4/29/2025	Envestnet Asset Management Inc.	31,430	$0.43M	0.0%	-16.5%	0.022%
4/29/2025	Bank of New York Mellon Corp	1,103,892	$15.01M	0.0%	-11.2%	0.760%
4/29/2025	VELA Investment Management LLC	27,771	$0.38M	0.1%	+77.6%	0.019%
4/28/2025	Principal Financial Group Inc.	1,081,578	$14.70M	0.0%	-4.4%	0.745%
4/28/2025	Teacher Retirement System of Texas	34,857	$0.47M	0.0%	-8.7%	0.024%
4/18/2025	Clarius Group LLC	368,995	$5.02M	0.3%	-10.0%	0.254%
4/15/2025	SG Americas Securities LLC	48,365	$0.66M	0.0%	+339.6%	0.033%
4/10/2025	Breakwater Capital Group	15,015	$0.20M	0.0%	N/A	0.010%
4/7/2025	GAMMA Investing LLC	7,953	$0.11M	0.0%	+253.8%	0.005%
3/18/2025	California State Teachers Retirement System	120,174	$2.45M	0.0%	-0.8%	0.083%
2/25/2025	Polar Asset Management Partners Inc.	551,092	$11.23M	0.1%	+1,240.9%	0.383%
2/19/2025	GF Fund Management CO. LTD.	3,022	$62K	0.0%	N/A	0.002%
2/17/2025	UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	3,582,874	$73.02M	0.0%	-4.4%	2.489%
2/17/2025	Woodline Partners LP	100,000	$2.04M	0.0%	N/A	0.069%
2/17/2025	Squarepoint Ops LLC	48,619	$0.99M	0.0%	+44.2%	0.034%
2/17/2025	Twinbeech Capital LP	254,586	$5.19M	0.1%	N/A	0.177%
2/17/2025	Two Sigma Advisers LP	15,100	$0.31M	0.0%	N/A	0.010%
2/17/2025	Two Sigma Investments LP	179,884	$3.67M	0.0%	+80.8%	0.125%
2/17/2025	Stempoint Capital LP	584,328	$11.91M	3.0%	+107.2%	0.406%
2/17/2025	Rafferty Asset Management LLC	141,310	$2.88M	0.0%	+20.1%	0.098%
2/17/2025	Point72 Asset Management L.P.	548,739	$11.18M	0.0%	+64.5%	0.381%
2/17/2025	Point72 Hong Kong Ltd	3,175	$65K	0.0%	N/A	0.002%
2/17/2025	Polar Asset Management Partners Inc.	551,092	$11.23M	0.2%	+1,240.9%	0.383%
2/17/2025	ProShare Advisors LLC	41,825	$0.85M	0.0%	+30.9%	0.029%
2/17/2025	Man Group plc	22,435	$0.46M	0.0%	-26.3%	0.016%
2/17/2025	Nuveen Asset Management LLC	355,057	$7.24M	0.0%	-50.4%	0.247%
2/17/2025	OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC	21,039	$0.43M	0.0%	-31.6%	0.015%
2/17/2025	Millennium Management LLC	404,224	$8.24M	0.0%	+571.8%	0.281%
2/17/2025	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	85,075	$1.73M	0.0%	+4.2%	0.059%
2/17/2025	Janus Henderson Group PLC	60,028	$1.23M	0.0%	+15.2%	0.042%
2/17/2025	Graham Capital Management L.P.	20,706	$0.42M	0.0%	+76.0%	0.014%
2/17/2025	Fred Alger Management LLC	91,807	$1.87M	0.0%	-24.3%	0.064%
2/17/2025	Deutsche Bank AG	277,853	$5.66M	0.0%	+15.8%	0.193%
2/17/2025	Crestline Management LP	4,310,732	$87.85M	2.9%	-3.4%	2.995%
2/17/2025	Brevan Howard Capital Management LP	17,917	$0.37M	0.0%	+60.5%	0.012%
2/17/2025	Balyasny Asset Management L.P.	416,074	$8.48M	0.0%	+822.4%	0.289%
2/17/2025	Bayesian Capital Management LP	18,820	$0.38M	0.0%	+135.3%	0.013%
2/17/2025	Bank of America Corp DE	270,333	$5.51M	0.0%	-22.4%	0.188%
2/17/2025	BNP Paribas Financial Markets	15,943	$0.33M	0.0%	-42.3%	0.011%
2/17/2025	Ameriprise Financial Inc.	16,743	$0.34M	0.0%	+126.3%	0.012%
2/17/2025	Algert Global LLC	39,015	$0.80M	0.0%	-19.8%	0.027%
2/17/2025	AXA S.A.	293,755	$5.99M	0.0%	-14.8%	0.204%
2/14/2025	Jane Street Group LLC	229,165	$4.67M	0.0%	-37.6%	0.159%
2/14/2025	Northern Trust Corp	1,201,518	$24.49M	0.0%	+10.7%	0.835%
2/14/2025	The Manufacturers Life Insurance Company	208,521	$4.25M	0.0%	+0.8%	0.145%
2/14/2025	Aquatic Capital Management LLC	15,694	$0.32M	0.0%	N/A	0.011%
2/14/2025	Susquehanna Fundamental Investments LLC	192,563	$3.92M	0.1%	N/A	0.134%
2/14/2025	Virtus ETF Advisers LLC	3,029	$62K	0.0%	-27.3%	0.002%
2/14/2025	Voya Investment Management LLC	54,813	$1.12M	0.0%	-5.2%	0.038%
2/14/2025	Price T Rowe Associates Inc. MD	3,058,615	$62.34M	0.0%	+6.6%	2.125%
2/14/2025	Dark Forest Capital Management LP	12,888	$0.26M	0.0%	N/A	0.009%
2/14/2025	Diadema Partners LP	60,000	$1.22M	0.5%	N/A	0.042%
2/14/2025	Hsbc Holdings PLC	33,390	$0.68M	0.0%	+24.2%	0.023%
2/14/2025	Tower Research Capital LLC TRC	11,288	$0.23M	0.0%	+2,519.0%	0.008%
2/14/2025	MetLife Investment Management LLC	76,050	$1.55M	0.0%	+5.9%	0.053%
2/14/2025	Capital Research Global Investors	5,477,211	$111.63M	0.0%	-30.7%	3.806%
2/14/2025	Dimensional Fund Advisors LP	1,855,036	$37.81M	0.0%	+19.0%	1.289%
2/14/2025	First Trust Advisors LP	65,442	$1.33M	0.0%	+260.9%	0.045%
2/13/2025	Marshall Wace LLP	1,788,737	$36.45M	0.0%	-9.1%	1.243%
2/13/2025	Guggenheim Capital LLC	48,131	$0.98M	0.0%	+133.5%	0.033%
2/13/2025	Walleye Capital LLC	24,820	$0.51M	0.0%	N/A	0.017%
2/13/2025	XTX Topco Ltd	16,087	$0.33M	0.0%	N/A	0.011%
2/13/2025	Barclays PLC	278,067	$5.67M	0.0%	+8.7%	0.193%
2/13/2025	Sterling Capital Management LLC	1,773	$36K	0.0%	+589.9%	0.001%
2/13/2025	Raymond James Financial Inc.	26,143	$0.53M	0.0%	N/A	0.018%
2/13/2025	Legal & General Group Plc	149,513	$3.05M	0.0%	-4.2%	0.104%
2/13/2025	Invesco Ltd.	121,478	$2.48M	0.0%	-41.1%	0.084%
2/13/2025	ADAR1 Capital Management LLC	44,826	$0.91M	0.2%	-56.0%	0.031%
2/13/2025	FMR LLC	8,019,746	$163.44M	0.0%	+2.4%	5.572%
2/13/2025	Envestnet Asset Management Inc.	37,622	$0.77M	0.0%	+34.5%	0.026%
2/13/2025	Wells Fargo & Company MN	88,933	$1.81M	0.0%	-5.1%	0.062%
2/12/2025	Cinctive Capital Management LP	130,445	$2.66M	0.1%	-12.5%	0.091%
2/12/2025	Bryce Point Capital LLC	20,550	$0.42M	0.1%	N/A	0.014%
2/12/2025	Groupama Asset Managment	110,207	$2.23M	0.0%	+41.2%	0.077%
2/12/2025	Trexquant Investment LP	60,656	$1.24M	0.0%	+147.2%	0.042%
2/12/2025	Geode Capital Management LLC	2,935,283	$59.84M	0.0%	-0.7%	2.040%
2/12/2025	Franklin Resources Inc.	74,862	$1.53M	0.0%	-6.5%	0.052%
2/12/2025	Alliancebernstein L.P.	3,315,642	$67.57M	0.0%	+8.8%	2.304%
2/12/2025	Pier 88 Investment Partners LLC	45,410	$0.93M	0.2%	-23.3%	0.032%
2/12/2025	Wellington Management Group LLP	9,847,951	$200.70M	0.0%	-8.2%	6.782%
2/12/2025	Schroder Investment Management Group	247,800	$5.02M	0.0%	+94.6%	0.172%
2/12/2025	Pictet Asset Management Holding SA	19,356	$0.39M	0.0%	+17.0%	0.013%
2/12/2025	Norges Bank	1,065,608	$21.72M	0.0%	N/A	0.740%
2/12/2025	BIT Capital GmbH	21,011	$0.43M	0.0%	-29.4%	0.015%
2/12/2025	JPMorgan Chase & Co.	222,983	$4.54M	0.0%	-5.3%	0.155%
2/12/2025	Artisan Partners Limited Partnership	1,054,523	$21.49M	0.0%	-3.3%	0.733%
2/11/2025	Pier Capital LLC	332,319	$6.77M	1.0%	+97.7%	0.231%
2/11/2025	Segall Bryant & Hamill LLC	289,075	$5.89M	0.1%	N/A	0.201%
2/11/2025	Prudential Financial Inc.	110,593	$2.25M	0.0%	-5.8%	0.077%
2/11/2025	Corebridge Financial Inc.	61,800	$1.26M	0.0%	-7.0%	0.043%
2/11/2025	Vanguard Group Inc.	12,021,230	$244.99M	0.0%	+7.6%	8.353%
2/11/2025	Fox Run Management L.L.C.	38,668	$0.79M	0.1%	N/A	0.027%
2/11/2025	KLP Kapitalforvaltning AS	26,100	$0.53M	0.0%	N/A	0.018%
2/11/2025	Sei Investments Co.	24,047	$0.49M	0.0%	-8.5%	0.017%
2/11/2025	American Century Companies Inc.	480,529	$9.79M	0.0%	+6.5%	0.334%
2/11/2025	Yiheng Capital Management L.P.	700,098	$14.27M	0.5%	+16.7%	0.486%
2/11/2025	Teacher Retirement System of Texas	38,178	$0.78M	0.0%	+18.6%	0.027%
2/11/2025	Intech Investment Management LLC	47,401	$0.97M	0.0%	+60.4%	0.033%
2/10/2025	Thrivent Financial for Lutherans	92,972	$1.90M	0.0%	-33.0%	0.065%
2/10/2025	Cibc World Markets Corp	11,633	$0.24M	0.0%	N/A	0.008%

Data available starting January 2016

See Full Table

Denali Therapeutics Inc., a biopharmaceutical company, develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases in the United States. The company's transport vehicle (TV)-enabled programs include DNL310 ETV, an IDS enzyme replacement therapy program for MPS II; TAK-594/DNL593 which is in Phase 1/II for frontotemporal dementia-granulin; DNL126 program for MPS IIIA; and DNL622 for MPS I, as well as other preclinical programs that target amyloid beta and HER2. Its brain-penetrant small molecule programs comprise BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; SAR443820/DNL788 RIPK1 inhibitor program for CNS disease; DNL343 eIF2B Activator program for amyotrophic lateral sclerosis; and SAR443122/DNL758 RIPK1 inhibitor program for peripheral inflammatory diseases. It also provides early stage program include TAK-594/DNL593 program for FTD-GRN; DNL126 program for MPS IIIA, a Sanfilippo Syndrome A; DNL622 for MPS I which is Hurler syndrome; Antibody Transport Vehicle Amyloid beta program; Oligonucleotide Transport Vehicle platform, a novel class of biotherapeutics to address the root cause of diseases through modulation of gene expression; and other TV-enabled discovery programs. The company has collaboration agreements with Biogen MA Inc. and Biogen International GmbH; Genzyme Corporation; Takeda Pharmaceutical Company Limited; F-star Gamma Limited, F-star Biotechnologische Forschungs-und Entwicklungsges m.b.H, and F-star Biotechnology Limited; and Genentech, Inc. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Today's Range

Now: $16.50

$16.07

$16.83

50 Day Range

MA: $14.74

$11.47

$20.75

52 Week Range

Now: $16.50

$10.57

$33.33

Volume

1,521,238 shs

Average Volume

1,082,452 shs

Market Capitalization

$2.40 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

1.58

Who are the company insiders with the largest holdings of Denali Therapeutics?: Denali Therapeutics' top insider investors include:
Ryan J Watts (CEO)
Alexander O Schuth (Insider)
Carole Ho (Insider)
Steve E Krognes (Director)
Vicki L Sato (Director)
Jennifer E Cook (Director)
Learn More about top insider investors at Denali Therapeutics.
Who are the major institutional investors of Denali Therapeutics?: Denali Therapeutics' top institutional shareholders include:
Bank of New York Mellon Corp — 0.76%
Principal Financial Group Inc. — 0.74%
Clarius Group LLC — 0.25%
SG Americas Securities LLC — 0.03%
Teacher Retirement System of Texas — 0.02%
Envestnet Asset Management Inc. — 0.02%
Learn More about top institutional investors of Denali Therapeutics stock.
Which major investors are selling Denali Therapeutics stock?: Within the previous quarter, DNLI stock was sold by these institutional investors:
Bank of New York Mellon Corp
Principal Financial Group Inc.
Clarius Group LLC
Envestnet Asset Management Inc.
Teacher Retirement System of Texas
During the last year, company insiders that have sold Denali Therapeutics company stock include:
Ryan J Watts (CEO)
Alexander O Schuth (Insider)
Carole Ho (Insider)
Steve E Krognes (Director)
Vicki L Sato (Director)
Jennifer E Cook (Director)
Learn More investors selling Denali Therapeutics stock.
Which major investors are buying Denali Therapeutics stock?: Within the last quarter, DNLI stock was purchased by institutional investors including:
SG Americas Securities LLC
Breakwater Capital Group
VELA Investment Management LLC
GAMMA Investing LLC