AMLX Insider Trading

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Insider Ownership Percentage: 11.70%

Insider Buying (Last 12 Months): $363,397.50

Insider Selling (Last 12 Months): $368,523.15

Amylyx Pharmaceuticals Insider Trading History Chart

Amylyx Pharmaceuticals Share Price & Price History

^$3.65

▲ +0.16 (4.58%)

As of 04/11/2025 05:00 PM ET

Days: 30 | 90 | 365

Amylyx Pharmaceuticals Insider Trading History

Transaction Date	Insider Name	Title	Buy/Sell	Number of Shares	Average Share Price	Total Transaction	Shares Held After Transaction
3/31/2025	Camille L Bedrosian	Insider	Sell	12,425	$3.47	$43,114.75	194,375
3/31/2025	James M Frates	CFO	Sell	10,896	$3.47	$37,809.12	290,988
3/31/2025	Joshua B Cohen	CEO	Sell	21,490	$3.47	$74,570.30	3,355,280
3/20/2025	Bernhardt G Zeiher	Director	Buy	10,000	$3.70	$37,000.00	10,000
2/24/2025	Gina Mazzariello	Insider	Sell	4,169	$3.15	$13,132.35	134,921
2/3/2025	Gina Mazzariello	Insider	Sell	3,678	$3.49	$12,836.22	139,090
2/3/2025	Joshua B Cohen	CEO	Sell	11,851	$3.47	$41,122.97	3,201,247
1/6/2025	Justin B Klee	CEO	Sell	7,471	$4.04	$30,182.84	3,176,788
9/30/2024	Camille L Bedrosian	Insider	Sell	11,442	$3.20	$36,614.40	143,801
9/30/2024	Justin B Klee	CEO	Sell	18,589	$3.20	$59,484.80	3,120,569
9/12/2024	James M Frates	CFO	Buy	40,000	$2.53	$101,200.00	233,464
9/3/2024	George M Milne Jr	Director	Buy	100,000	$2.20	$220,000.00	858,571
5/15/2024	Gina Mazzariello	Insider	Sell	10,455	$1.88	$19,655.40	151,477
5/14/2024	Daphne Quimi	Director	Buy	2,750	$1.89	$5,197.50	2,750
3/5/2024	Gina Mazzariello	Insider	Sell	1,540	$18.73	$28,844.20	81,372
3/5/2024	James M Frates	CFO	Sell	1,792	$18.73	$33,564.16	134,784
3/5/2024	Joshua B Cohen	CEO	Sell	4,135	$18.73	$77,448.55	3,023,002
2/23/2024	Gina Mazzariello	Insider	Sell	2,838	$18.76	$53,240.88	46,245
1/9/2024	James M Frates	CFO	Sell	2,716	$16.33	$44,352.28	112,035
1/9/2024	Justin B Klee	CEO	Sell	5,841	$16.33	$95,383.53	2,836,776
1/9/2024	Patrick D Yeramian	Insider	Sell	2,812	$16.33	$45,919.96	205,605
5/16/2023	James M Frates	CFO	Sell	32,500	$26.94	$875,550.00	55,676
5/15/2023	Patrick D Yeramian	Insider	Sell	11,965	$29.03	$347,343.95	208,417
4/17/2023	Patrick D Yeramian	Insider	Sell	49,579	$30.54	$1,514,142.66	208,417
3/29/2023	Morningside Venture Investment	Major Shareholder	Sell	29,048	$30.45	$884,511.60	6,997,302
3/27/2023	Morningside Venture Investment	Major Shareholder	Sell	60,964	$30.50	$1,859,402.00	7,126,350
3/21/2023	Morningside Venture Investment	Major Shareholder	Sell	63,448	$31.91	$2,024,625.68	7,187,314
3/16/2023	George M Milne Jr	Director	Sell	35,000	$31.89	$1,116,150.00	862,021
3/16/2023	James M Frates	CFO	Sell	32,500	$31.89	$1,036,425.00	1,509
3/16/2023	Justin B Klee	CEO	Sell	100,000	$31.86	$3,186,000.00	2,792,617
3/16/2023	Morningside Venture Investment	Major Shareholder	Sell	9,122	$32.55	$296,921.10	7,250,762
3/16/2023	Patrick D Yeramian	Insider	Sell	54,627	$31.87	$1,740,962.49	149,672
3/14/2023	Morningside Venture Investment	Major Shareholder	Sell	70,714	$34.54	$2,442,461.56	7,409,884
3/2/2023	Morningside Venture Investment	Major Shareholder	Sell	50,000	$33.75	$1,687,500.00	7,480,598
2/24/2023	Gina Mazzariello	Insider	Sell	3,586	$34.49	$123,681.14	37,414
2/22/2023	Morningside Venture Investment	Major Shareholder	Sell	50,000	$34.73	$1,736,500.00	7,530,598
9/8/2022	Global Investors Lp Viking	Major Shareholder	Sell	700,000	$29.37	$20,559,000.00	2,075,470

See Full Table

SEC Filings (Institutional Ownership Changes) for Amylyx Pharmaceuticals (NASDAQ:AMLX)

95.84% of Amylyx Pharmaceuticals stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

Amylyx Pharmaceuticals Institutional Trading History

Reporting Date	Hedge Fund	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
4/10/2025	Hennion & Walsh Asset Management Inc.	83,236	$0.30M	0.0%	-8.1%	0.094%
3/24/2025	Wellington Management Group LLP	209,708	$0.79M	0.0%	N/A	0.237%
2/20/2025	Mackenzie Financial Corp	111,310	$0.42M	0.0%	+234.9%	0.162%
2/18/2025	Alpine Global Management LLC	12,017	$45K	0.0%	N/A	0.018%
2/17/2025	Vident Advisory LLC	10,862	$41K	0.0%	-30.2%	0.016%
2/17/2025	Two Sigma Advisers LP	241,400	$0.91M	0.0%	-22.0%	0.352%
2/17/2025	Two Sigma Investments LP	651,517	$2.46M	0.0%	+77.4%	0.950%
2/17/2025	State of Wyoming	16,077	$61K	0.0%	-37.6%	0.023%
2/17/2025	Point72 Asia Singapore Pte. Ltd.	72,863	$0.28M	0.1%	-12.8%	0.106%
2/17/2025	Man Group plc	100,059	$0.38M	0.0%	-23.5%	0.146%
2/17/2025	OMERS ADMINISTRATION Corp	66,000	$0.25M	0.0%	N/A	0.096%
2/17/2025	Orbimed Advisors LLC	348,000	$1.32M	0.0%	N/A	0.508%
2/17/2025	Millennium Management LLC	594,236	$2.25M	0.0%	+30.1%	0.867%
2/17/2025	Jacobs Levy Equity Management Inc.	314,939	$1.19M	0.0%	-34.2%	0.459%
2/17/2025	D. E. Shaw & Co. Inc.	306,744	$1.16M	0.0%	-55.6%	0.447%
2/17/2025	Cubist Systematic Strategies LLC	472,397	$1.79M	0.0%	+862.5%	0.689%
2/17/2025	Bridgeway Capital Management LLC	146,500	$0.55M	0.0%	+12.7%	0.214%
2/17/2025	Bank of America Corp DE	2,426,263	$9.17M	0.0%	+165.9%	3.539%
2/17/2025	Ameriprise Financial Inc.	50,428	$0.19M	0.0%	N/A	0.074%
2/17/2025	Alyeska Investment Group L.P.	823,420	$3.11M	0.0%	-59.3%	1.201%
2/17/2025	Almitas Capital LLC	2,032,370	$7.68M	1.7%	+2.2%	2.965%
2/17/2025	683 Capital Management LLC	1,930,000	$7.30M	0.5%	-3.5%	2.815%
2/14/2025	Boxer Capital Management LLC	1,750,000	$6.62M	0.6%	N/A	2.553%
2/14/2025	Jane Street Group LLC	765,475	$2.89M	0.0%	+122.4%	1.117%
2/14/2025	Schonfeld Strategic Advisors LLC	193,931	$0.73M	0.0%	+16.5%	0.283%
2/14/2025	Nantahala Capital Management LLC	1,452,153	$5.49M	0.2%	+3.4%	2.118%
2/14/2025	Northern Trust Corp	106,564	$0.40M	0.0%	+11.8%	0.155%
2/14/2025	Tudor Investment Corp ET AL	33,687	$0.13M	0.0%	N/A	0.049%
2/14/2025	Boothbay Fund Management LLC	80,543	$0.30M	0.0%	-5.8%	0.117%
2/14/2025	Alpine Global Management LLC	12,017	$45K	0.0%	N/A	0.018%
2/14/2025	Hsbc Holdings PLC	11,566	$43K	0.0%	-81.3%	0.017%
2/14/2025	Tower Research Capital LLC TRC	45,987	$0.17M	0.0%	+377.0%	0.067%
2/14/2025	Dimensional Fund Advisors LP	54,114	$0.21M	0.0%	N/A	0.079%
2/14/2025	Alpha Wave Global LP	148,627	$0.56M	0.3%	-77.8%	0.217%
2/13/2025	Marshall Wace LLP	184,678	$0.70M	0.0%	-35.0%	0.269%
2/13/2025	Jump Financial LLC	104,342	$0.39M	0.0%	N/A	0.152%
2/13/2025	Guggenheim Capital LLC	35,868	$0.14M	0.0%	+132.9%	0.052%
2/13/2025	XTX Topco Ltd	53,376	$0.20M	0.0%	+12.0%	0.078%
2/13/2025	Mariner LLC	50,539	$0.19M	0.0%	-10.3%	0.074%
2/13/2025	Barclays PLC	74,845	$0.28M	0.0%	-11.5%	0.109%
2/13/2025	Renaissance Technologies LLC	464,400	$1.76M	0.0%	+70.9%	0.677%
2/13/2025	Federated Hermes Inc.	202,316	$0.77M	0.0%	+8.6%	0.295%
2/13/2025	Wedbush Securities Inc.	19,914	$75K	0.0%	N/A	0.029%
2/12/2025	Landscape Capital Management L.L.C.	49,661	$0.19M	0.0%	N/A	0.072%
2/12/2025	Aldebaran Capital LLC	262,753	$0.99M	0.9%	-2.6%	0.383%
2/12/2025	RPO LLC	12,136	$46K	0.0%	N/A	0.018%
2/12/2025	ExodusPoint Capital Management LP	106,237	$0.40M	0.0%	N/A	0.155%
2/12/2025	Geode Capital Management LLC	567,903	$2.15M	0.0%	+3.1%	0.828%
2/12/2025	Wellington Management Group LLP	209,708	$0.79M	0.0%	N/A	0.306%
2/12/2025	JPMorgan Chase & Co.	55,606	$0.21M	0.0%	-60.4%	0.081%
2/11/2025	EntryPoint Capital LLC	13,909	$53K	0.0%	N/A	0.020%
2/11/2025	Fox Run Management L.L.C.	11,788	$45K	0.0%	N/A	0.017%
2/11/2025	American Century Companies Inc.	59,310	$0.22M	0.0%	+181.8%	0.087%
2/10/2025	Kennondale Capital Management LLC	134,445	$0.51M	0.4%	N/A	0.196%
2/10/2025	Connor Clark & Lunn Investment Management Ltd.	1,263,353	$4.78M	0.0%	+43.4%	1.843%
2/6/2025	Charles Schwab Investment Management Inc.	298,949	$1.13M	0.0%	-1.1%	0.436%
2/4/2025	Y Intercept Hong Kong Ltd	14,809	$56K	0.0%	N/A	0.022%
1/30/2025	Blue Trust Inc.	6,987	$26K	0.0%	+232.1%	0.010%
1/24/2025	abrdn plc	1,722,805	$6.51M	0.0%	-12.6%	2.513%
1/22/2025	Blue Trust Inc.	6,987	$26K	0.0%	+232.1%	0.010%
1/17/2025	SG Americas Securities LLC	15,958	$60K	0.0%	-72.2%	0.023%
1/15/2025	Hennion & Walsh Asset Management Inc.	90,619	$0.34M	0.0%	-20.9%	0.132%
12/26/2024	JPMorgan Chase & Co.	140,559	$0.46M	0.0%	+144.4%	0.205%
11/19/2024	Barclays PLC	84,572	$0.27M	0.0%	+91.1%	0.123%
11/16/2024	Geode Capital Management LLC	551,039	$1.79M	0.0%	+17.5%	0.804%
11/15/2024	Barclays PLC	84,572	$0.27M	0.0%	+91.1%	0.123%
11/15/2024	XTX Topco Ltd	47,672	$0.15M	0.0%	-77.4%	0.070%
11/15/2024	Jane Street Group LLC	344,173	$1.12M	0.0%	-29.9%	0.502%
11/15/2024	Jacobs Levy Equity Management Inc.	478,440	$1.55M	0.0%	-18.8%	0.698%
11/14/2024	Walleye Capital LLC	670,594	$2.17M	0.0%	+986.5%	0.978%
11/13/2024	Alpha Wave Global LP	669,487	$2.17M	0.7%	N/A	0.977%
11/13/2024	FMR LLC	221,001	$0.72M	0.0%	+292.0%	0.322%
11/12/2024	Charles Schwab Investment Management Inc.	302,270	$0.98M	0.0%	-42.1%	0.444%
11/8/2024	Connor Clark & Lunn Investment Management Ltd.	880,745	$2.85M	0.0%	+41.6%	1.294%
10/25/2024	China Universal Asset Management Co. Ltd.	13,094	$42K	0.0%	+63.9%	0.019%
10/25/2024	abrdn plc	1,972,242	$6.39M	0.0%	+1,567.9%	2.900%
10/23/2024	Hennion & Walsh Asset Management Inc.	114,534	$0.37M	0.0%	-3.7%	0.168%
9/16/2024	Point72 DIFC Ltd	25,953	$49K	0.0%	-47.0%	0.038%
9/16/2024	Cubist Systematic Strategies LLC	166,548	$0.32M	0.0%	-5.4%	0.245%
9/16/2024	Point72 Asia Singapore Pte. Ltd.	82,042	$0.16M	0.0%	N/A	0.121%
8/29/2024	Maven Securities LTD	100,000	$0.19M	0.0%	+300.0%	0.147%
8/16/2024	Algert Global LLC	24,814	$47K	0.0%	N/A	0.036%
8/16/2024	Almitas Capital LLC	1,903,851	$3.62M	1.5%	N/A	2.800%
8/15/2024	Mackenzie Financial Corp	57,923	$0.11M	0.0%	-20.2%	0.085%
8/15/2024	Millennium Management LLC	1,535,178	$2.92M	0.0%	-38.9%	2.257%
8/15/2024	AQR Capital Management LLC	3,340,943	$6.35M	0.0%	+2,768.0%	4.913%
8/15/2024	Point72 Asia Singapore Pte. Ltd.	82,042	$0.16M	0.0%	N/A	0.121%
8/14/2024	Squarepoint Ops LLC	272,576	$0.52M	0.0%	+71.1%	0.401%
8/14/2024	Cubist Systematic Strategies LLC	166,548	$0.32M	0.0%	-5.4%	0.245%
8/14/2024	Point72 DIFC Ltd	25,953	$49K	0.0%	-47.0%	0.038%
8/12/2024	XTX Topco Ltd	210,612	$0.40M	0.0%	N/A	0.310%
8/12/2024	Hsbc Holdings PLC	76,261	$0.15M	0.0%	+57.9%	0.112%
8/9/2024	Renaissance Technologies LLC	811,488	$1.54M	0.0%	+15.2%	1.193%
8/8/2024	American Century Companies Inc.	19,041	$36K	0.0%	-95.0%	0.028%
8/6/2024	Acadian Asset Management LLC	1,211,617	$2.30M	0.0%	N/A	1.782%
8/1/2024	Rhumbline Advisers	28,779	$55K	0.0%	-58.5%	0.042%
7/26/2024	Allspring Global Investments Holdings LLC	28,785	$55K	0.0%	+88.4%	0.042%
7/20/2024	Hennion & Walsh Asset Management Inc.	118,983	$0.23M	0.0%	+5.4%	0.175%
7/12/2024	SG Americas Securities LLC	55,836	$0.11M	0.0%	+113.6%	0.082%
7/10/2024	CWM LLC	28,643	$54K	0.0%	+104.2%	0.042%

Data available starting January 2016

See Full Table

Amylyx Pharmaceuticals, Inc., a commercial-stage biotechnology company, engages in the discovery and development of treatment for amyotrophic lateral sclerosis (ALS) and neurodegenerative diseases. The company's products include RELYVRIO, a dual UPR-Bax apoptosis inhibitor composed of sodium phenylbutyrate and taurursodiol for the treatment of ALS in adults in the United States and marketed as ALBRIOZA for the treatment of ALS in Canada. It is also developing AMX0114 for other neurodegenerative diseases. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

Today's Range

Now: $3.65

$3.42

$3.68

50 Day Range

MA: $3.54

$3.00

$3.91

52 Week Range

Now: $3.65

$1.58

$7.27

Volume

562,243 shs

Average Volume

1,314,091 shs

Market Capitalization

$323.40 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

N/A

Who are the company insiders with the largest holdings of Amylyx Pharmaceuticals?: Amylyx Pharmaceuticals' top insider shareholders include:
Joshua B Cohen (CEO)
Justin B Klee (CEO)
George M Milne Jr (Director)
James M Frates (CFO)
Patrick D Yeramian (Insider)
Camille L Bedrosian (Insider)
Gina Mazzariello (Insider)
Bernhardt G Zeiher (Director)
Daphne Quimi (Director)
Learn More about top insider investors at Amylyx Pharmaceuticals.
Who are the major institutional investors of Amylyx Pharmaceuticals?: Amylyx Pharmaceuticals' top institutional investors include:
Hennion & Walsh Asset Management Inc. — 0.09%
Learn More about top institutional investors of Amylyx Pharmaceuticals stock.
Which institutional investors are selling Amylyx Pharmaceuticals stock?: During the previous quarter, AMLX stock was sold by these institutional investors:
Hennion & Walsh Asset Management Inc.
Within the last year, company insiders that have sold Amylyx Pharmaceuticals company stock include:
Joshua B Cohen (CEO)
Justin B Klee (CEO)
George M Milne Jr (Director)
James M Frates (CFO)
Patrick D Yeramian (Insider)
Learn More investors selling Amylyx Pharmaceuticals stock.